Fourth, this study may lead to measurement bias or omission. In conclusion, we found that pregnant women with elevated TSH levels had an increased risk of miscarriage in early pregnancy. The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported.
The authors gratefully acknowledge the invaluable contributions of doctors from the Gynecology and Obstetrics clinics in the 13 hospitals in Liaoning Province and are indebted to the residents who participated in this study.
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Advanced Search Help. Maternal TSH levels at first trimester and subsequent spontaneous miscarriage: a nested case—control study in Endocrine Connections. Correspondence should be addressed to W Teng or Z Shan: twp vip.
Open access. Search date: August 22, Already a member or subscriber? Log in. Interested in AAFP membership? Learn more. Address correspondence to Leo A. Hwy 98, Pensacola, FL e-mail: leo. Reprints are not available from the authors. The views expressed in this article are those of the authors and do not necessarily reflect the official policy or position of the U. Navy Medical Corps, the U. Navy, or the U. Department of Defense. Interventions for clinical and subclinical hypothyroidism in pregnancy.
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Author disclosure: No relevant financial affiliations. C 3 , 6 Targeted screening for thyroid disease should be performed in pregnant women at high risk, including those with a history of thyroid disease, type 1 diabetes mellitus, or other autoimmune disease; current or past use of thyroid therapy; or a family history of autoimmune thyroid disease.
C 2 , 3 Hypothyroidism during pregnancy should be treated with levothyroxine, with a serum TSH goal of less than 2. This study investigated the rate of preterm early delivery and pregnancy loss in women without hypothyroidism but with a TSH in the upper range of normal TSH 2.
What was the aim of the study? The aim of this study was to evaluate the rate of preterm delivery and pregnancy loss in women without hypothyroidism who had a TSH between 2. Who was studied? The women in this study are a subgroup of a larger prospective study of thyroid function and pregnancy. This study included women who were all negative for anti-thyroid antibodies ie no evidence of intrinsic thyroid disease and had a TSH less than or equal to 5.
Hyperthyroid women were excluded. How was the study done? They were then followed normally throughout pregnancy. Pregnancy outcomes were recorded and the rates of pregnancy loss and preterm delivery were compared between women in the two groups. What were the results of the study? A total of The remaining women
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